Selected Publications (first or corresponding author; *equal contribution)
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Hu Z, Kovach AE, Yelapantulla V, Ostrow D, Doan A, Ji J, Schmidt RJ, Gu Z*✉, Bhojwani D and Raca G*✉.
Transcriptome Sequencing Allows Comprehensive Genomic Characterization of Pediatric B-Cell Acute Lymphoblastic Leukemia in an Academic Clinical Laboratory.
J Mol Diagn. Epub 2023 Nov 18.
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Gu Z & Izraeli S. All about Down syndrome ALL.
Blood. 142, 126-128. 2023
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Hu Z, Jia Z, Liu J, Mao A, Han H, Gu Z✉.
MD-ALL: an Integrative Platform for Molecular Diagnosis of B-Acute Lymphoblastic Leukemia.
Haematologica. [Online ahead of print] 2023.
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Jia Z, Gu Z✉. PAX5 alterations in B-cell acute lymphoblastic leukemia.
Frontiers in Oncology. 2022.
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BaĆinka J, Hu Z, Wang L, ..., Gu Z*✉, Mullighan CG*✉.
RNAseqCNV: analysis of large-scale copy number variations from RNA-seq data.
Leukemia. 2022; 36(6): 1492-1498.
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Montefiori LE*, Bendig S*, Gu Z*, Dobson SM*, ..., Klco JM, Haferlach C✉, Mullighan CG✉.
Enhancer hijacking drives oncogenic BCL11B expression in lineage ambiguous stem cell leukemia.
Cancer Discovery. 2021; 11(11): 2846-2867
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Waanders E*, Gu Z*, Chen X*, ..., Dick JE, Kuiper RP, Mullighan CG✉.
Mutational landscape and patterns of clonal evolution in relapsed pediatric acute lymphoblastic leukemia.
Blood Cancer Discovery. 2020; 21:1-16
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Gu Z*, Churchman ML*, Roberts KG*, ..., Loh ML, Hunger SP, Mullighan CG✉.
PAX5-driven Subtypes of B-cell Acute Lymphoblastic Leukemia.
Nature Genetics. 2019; 51(2):296-307
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Alexander TB*, Gu Z*, Iacobucci I*, ..., Hunger SP, Inaba H✉, Mullighan CG✉.
The genetic basis and cell of origin of mixed phenotype acute leukemia.
Nature. 2018; 562(7727):373-379
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Gu Z, Mullighan CG✉.
ShinyCNV: a Shiny/R application to view and annotate DNA copy number variations.
Bioinformatics. 2018; 35(1):126-129.
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Gu Z, Churchman M, Roberts K, ..., L. Loh M, P. Hunger SP, Mullighan CG✉.
Genomic analyses identify recurrent MEF2D fusions in acute lymphoblastic leukaemia.
Nature Communications. 2016; 7:13331
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Jiang L*, Gu Z*, Yan ZX*, Zhao X*, ..., Chen Z✉, Chen SJ✉.
Exome sequencing identifies somatic mutations of DDX3X in natural killer/T-cell lymphoma.
Nature Genetics. 2015; 47(9):1061-6
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Yan XJ*, Xu J*, Gu Z*, Pan CM*, Lu G*, ..., Chen Z✉, Chen SJ✉.
Exome sequencing identifies somatic mutations of DNA methyltransferase gene DNMT3A in acute monocytic leukemia.
Nature Genetics. 2011; 43(4):309-15
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Xu L*, Gu Z*, Li Y*, Zhang JL*, Chang CK*, ..., Chen Z✉ & Chen SJ✉.
Genomic Landscape of CD34+ Hematopoietic Cells in Myelodysplastic Syndrome and Gene Mutation Profiles as Prognostic Markers.
Proc Natl Acad Sci U S A. 2014; 111(23):8589-94